IV Ketamine & Lidocaine for Neuropathic Pain
Advanced relief for chronic nerve pain and mood-related symptoms when other treatments have failed.
Neuropathic pain results from damage to the nervous system and can significantly impact your quality of life. At Silver Pain Centre, we offer IV Ketamine and Lidocaine infusions to help reduce pain, improve function, and alleviate associated symptoms like anxiety and depression. This dual-therapy approach provides hope for those living with complex conditions such as CRPS, fibromyalgia, diabetic neuropathy, and treatment-resistant mood disorders.
What Is Neuropathic Pain?
Neuropathic pain is a complex, chronic condition caused by damage or dysfunction in the central or peripheral nervous system. Unlike typical pain from injury or inflammation, neuropathic pain stems from how the nerves transmit signals to the brain—often leading to burning, tingling, or shooting sensations that are difficult to control with standard medications.
When traditional treatments fail to bring relief, IV infusion therapy with Ketamine and/or Lidocaine offers a promising alternative to reduce nerve-related pain and improve quality of life.
Common causes include:
Spinal Cord Injury
Stroke or Head Trauma
Post-surgical Nerve Damage
Complex Regional Pain Syndrome (CRPS)
Fibromyalgia
Diabetic Neuropathy
Nerve Compression or Inflammation
What Are Ketamine and Lidocaine Infusions?
Ketamine is a non-opioid anesthetic with sedative, pain-relieving, and psychedelic properties. It targets the NMDA receptors in the nervous system, helping to “reset” pain pathways and reduce symptoms of depression.
Lidocaine is a local anesthetic that calms overactive nerves. It is often used in combination with ketamine to enhance pain relief without cognitive effects.
These therapies are particularly beneficial for patients with treatment-resistant neuropathic pain or overlapping mood disorders.
Conditions That May Benefit From Infusion Therapy:
Chronic Diabetic Neuropathy
Complex Regional Pain Syndrome (CRPS)
Fibromyalgia
Cluster Headaches and Migraines
Medically-Resistant Depression
OCD/PTSD
Severe Anxiety
What to Expect During Your Infusion
Ketamine Infusion:
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Duration: 4–5 hours
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Sedative effect may cause sleep or deep relaxation
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Continuous monitoring by trained nursing staff
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You must fast (no food or drink) for 8 hours before treatment
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A responsible adult must accompany you and stay with you post-treatment
Lidocaine Infusion:
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Duration: 45 minutes with a 15-minute recovery
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Often used in combination with Ketamine
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Minimal cognitive effects
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Safe, well-tolerated in most patients
Preparation Includes:
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Clear fluids allowed up to 2 hours before
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Light snack (e.g. toast, fruit) up to 6 hours before
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No heavy food (fats/proteins) 9 hours prior
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Take most regular medications unless advised otherwise
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Bring headphones/music for comfort
Why Choose Infusion Therapy for Neuropathic Pain?
Clinically Proven Relief
Backed by published research showing safety and effectiveness for pain and mood disorders.
May Be Covered by OHIP/ Insurance
Lidocaine may be covered under OHIP; Ketamine is not. Our team will guide you through the options.
Dual-Agent Approach
Combining Ketamine and Lidocaine may enhance relief and minimize medication dependency.
Experienced Care Team
Treatments are delivered by trained pain specialists in a monitored medical setting.
Non-Opioid, Non-Surgical
A powerful alternative for patients who do not respond to traditional painkillers.
Lasting Results
Many patients experience relief lasting weeks to months after just a few infusions.
Frequently Asked Questions
How Long Does Relief Last?
Relief from IV Ketamine or Lidocaine can begin within days of treatment. Duration and response vary based on your condition and treatment frequency.
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Most patients feel relief within 1–3 days
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Effects may last weeks to several months
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Benefits often increase after the first 3–5 sessions
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Booster infusions may be needed every few months
How Many Treatments Are Needed?
Treatment plans are individualized, but most patients start with a series of infusions and continue as needed.
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Initial protocol: 5 infusions spaced 1–4 weeks apart
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Maintenance or “booster” infusions may follow
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Your physician will assess whether to continue based on response
Why Choose Silver Pain Centre?
At Silver Pain Centre, we specialize in advanced, personalized care for chronic pain and neuropatthic pain.
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One of the few clinics in Ontario offering both Ketamine and Lidocaine infusions
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A dedicated medical team with advanced expertise in nerve-related pain and mental health
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Safe, monitored environment for all infusions
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Personalized treatment plans based on condition, diagnosis, and response
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Convenient North Toronto location with free parking and shorter wait times
What to Expect at Silver Pain Centre?
We make the process easy—from your first consultation to your post-treatment recovery.
Complete Your Self-Referral: Submit our online form. A physician will review your request within 72 hours and contact you for a consultation.
Consultation With a Specialist: We’ll assess your symptoms, history, and goals to determine if infusion therapy is right for you.
Receive Treatment: Infusions are administered in a calm, medically-supervised space. Treatment duration ranges from 45 minutes (Lidocaine) to 4–5 hours (Ketamine).
Resume Normal Life: You’ll be monitored after treatment and must be picked up by a responsible adult. Many patients return to light activities the next day, with continued improvement in pain and mood symptoms.
Is this treatment right for you or your patient?
Our Medical Director is here to help. If you have a question about whether this treatment is appropriate for yourself or someone in your care, submit it below and our team will review your inquiry.
Your Partner in Pain Management
At Silver Pain Centre, we understand the challenges of chronic pain. We offer comprehensive care for a wide range of conditions, including joint and back pain, chronic headaches, nerve pain, muscle injuries, post-surgical pain, sports injuries, and more.
Located in North Toronto, our modern 20,000 sq. ft. facility offers shorter wait times and free parking, making access to care easier. With a patient-centered, multidisciplinary approach, we create tailored treatment plans to deliver long-lasting relief when traditional methods have not succeeded.
Explore Silver Pain Centre Difference
Discover Relief from Neuropathic Pain—Start Your Self-Referral Today
If chronic nerve pain or treatment-resistant symptoms are affecting your life, infusion therapy with Ketamine and/or Lidocaine may help. Our team will review your self-referral and guide you through a personalized consultation to see if you’re a candidate for this advanced treatment.